Overuse is defined as using medications for more than 2 or 3 days per week on a regular basis for 3 or more months. Some drugs can cause MOH with even 10 days of use per month regularly, such as ergotamine, triptans or opioids, while other drugs require 15 or more days of use per month, such as simple analgesics or combination of acute drugs.
Patients suffering from MOH can be difficult to treat, and may require detoxification from the offending medication. This is one condition that can be effectively treated using a multi-pronged approach, using a combination of preventative medications, homeopathy, Ayurvedic medicine, yoga, dietary manipulation and other therapies in a personalized method tailored to each individual headache sufferer. A cookie-cutter, one technique-fits-all approach is not an ideal method for addressing this type of condition, and is most likely doomed for failure. In other words, the treatment has to be designed for each patient individually, based upon his or her unique circumstances.